History of the AADC Research Trust

1990 

  • The first cases of AADC deficiency were described by Hyland and Clayton

2006 

  • The AADC Research Trust was formed and fundraising begins
  • Website www.aadcresearch.org launched

2007 

  • The first meeting of the Trust’s medical and scientific advisory panel
  •  The Trust’s first fully funded PhD studentship begins at the UCL Institute of Neurology
  •  Part-funding for a new HPLC machine for the diagnosis and research of AADC deficiency
  •  Small grant award to Georg Hoffman for AADC treatment research
  •  International network and forum opens for AADC affected families

2008 

  • Grant Awarded to Dr Wang-Tso Lee to develop a new model of AADC deficiency
  •  The Trust engages help of Prof. Chris Harris to examine the eyes of AADC patients
  •  Plasma AADC enzyme assay established in the UK following funding from the Trust
  •  Nenad Blau begins work to establish a clinical database of AADC deficiency
  •  Trust funds medical professionals to attend a meeting at University Putra Malaysia
  •  Malaysian student trained in biochemical diagnosis of neurotransmitters at UCL

2009 

  • First research article funded by the Trust published by G Allen, J Land and S Heales
  • The JAKE international database of AADC deficiency launched
  • Findings from the JAKE database published in the journal Neurology
  • Research grant awarded to M Verbeek and M Willemsen to study renal dopamine synthesis

2010 

  • Trust funded research article published on urinary dopamine (Wassenberg et al)
  • Trust funded research article published on pyridoxal 5’-phosphate (Allen et al)
  •  eBear’s Attic AADC Research trust Charity Shop opens in Warlingham, UK

2011 

  • First AADC Research Trust International AADC Conference
  • AADC Research Trust funded student George Allen is awarded his PhD

2012 

  • Trust funded research article published on urinary dopamine (Wassenberg et al)

2013 

  • Trust funded research article published on dopamine and glutathione (Allen et al)
  • Grant awarded to Dr Manju Kurian for an induced pluripotent stem cells research project
  •  eBear’s Tea Room & Charity Boutique opens in Hamsey Green, UK

2014 

  • Funding provided to Dr Bankiewicz to aid gene therapy trial FDA application
  • Grant awarded to Dr Thomas Opladen to provide funding for the iNTD project
  • Second AADC Research Trust International AADC Conference

2015 

  • Grant awarded to Prof. Voltattorni for molecular research into AADC deficiency